Current concepts of diagnosis and therapy, West. W.: Primary aldosteronism: A new clinical syndrome, J. L., et al.: Late onset 21-hydroxylase deficiency mimicking idiopathic hirsutism or polycystic ovarian disease, Ann. P.: The regulation of aldosterone secretion in primary aldosteronism, Am. W.: Current concepts: Pheochromocytoma: Diagnosis, localization and management, N.

I., et al.: Adult onset familial adrenal 21-hydroxylase deficiency, Am. N.: Clinical and laboratory findings and results of therapy in 58 patients with adrenocortical tumors admitted to a single medical center (1951–1978), Am. A., et al.: Cushing’s syndrome: Problems in diagnosis, Medicine 60:25, 1981.Īxelrod, L.: Glucocorticoid therapy, Medicine 55:39, 1976.īertagna, C., and Orth, D. This process is experimental and the keywords may be updated as the learning algorithm improves.Īron, D. These keywords were added by machine and not by the authors. Second, although norepinephrine can be secreted by the tissues of sympathetic nervous system as well as by the medulla, the enzymatic machinery required to produce epinephrine is possessed only by the adrenal medulla and the organ of Zuckerkandl, a structure composed of chromaffin-staining cells situated near the origin of the inferior mesenteric artery and often extending alongside the aorta until its bifurcation. In this regard, the medulla can be regarded as a large “master ganglion” of the sympathetic system. First, the rate of production and release of catecholamines by the adrenal medulla are several hundredfold greater in comparison to the tissue of the sympathetic nervous system elsewhere. Although this property is shared by sympathetic nervous tissue throughout the entire length of the sympathetic chain, the adrenal medulla differs in two important respects. The adrenal medulla synthesizes and releases catecholamines.

Adrenal medulla releases